Ca2+-induced myelin pathology precedes axonal spheroid formation and is mediated in part by store-operated Ca2+ entry after spinal cord injury

Ca2+-induced myelin pathology precedes axonal spheroid formation and is mediated in part by store-operated Ca2+ entry after spinal cord injury

[INLINE:1] The formation of axonal spheroid is a common feature following spinal cord injury. To further understand the source of Ca2+ that mediates axonal spheroid formation, we used our previously characterized ex vivo mouse spinal cord model that allows precise perturbation of extracellular Ca2+....

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Bibliographic Details
Main Authors: Spencer Ames, Kia Adams, Mariah E Geisen, David P Stirling
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Neural Regeneration Research
Subjects:
axonal degeneration; axonal spheroid formation; ionomycin; store-operated calcium entry; myelin; nile red; peri-axonal swelling
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=12;spage=2720;epage=2726;aulast=Ames

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=12;spage=2720;epage=2726;aulast=Ames

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