Phosphodiesterase 5 Inhibitor Potentiates Epigallocatechin 3-O-Gallate-Induced Apoptotic Cell Death via Activation of the cGMP Signaling Pathway in Caco-2 Cells

Phosphodiesterase 5 Inhibitor Potentiates Epigallocatechin 3-O-Gallate-Induced Apoptotic Cell Death via Activation of the cGMP Signaling Pathway in Caco-2 Cells

Epigallocatechin 3-<i>O</i>-gallate (EGCG) is a predominant component in green tea with various health benefits. The 67 kDa laminin receptor (67LR) is a nonintegrin cell surface receptor that is overexpressed in various types of cancer; 67LR was identified a cell surface EGCG target that...

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Bibliographic Details
Main Authors: Jaehoon Bae, Kwanwoo Lee, Ji-Sun Park, Jinseok Jung, Hirofumi Tachibana, Yoshinori Fujimura, Motofumi Kumazoe, Jae Sung Lim, Young-Chang Cho, Seung-Jae Lee, Su-Jin Park
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Current Issues in Molecular Biology
Subjects:
epigallocatechin 3-<i>O</i>-gallate
vardenafil
phosphodiesterase 5
cyclic guanosine monophosphate
endothelial nitric oxide synthase
Online Access:https://www.mdpi.com/1467-3045/44/12/426

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https://www.mdpi.com/1467-3045/44/12/426

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