BMP-6 promotes type 2 immune response during enhancement of rat mandibular bone defect healing

BMP-6 promotes type 2 immune response during enhancement of rat mandibular bone defect healing

IntroductionBone morphogenetic proteins (BMPs) are used as key therapeutic agents for the treatment of difficult fractures. While their effects on osteoprogenitors are known, little is known about their effects on the immune system.MethodsWe used permutations of BMP-6 (B), vascular endothelial growt...

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Bibliographic Details
Main Authors: Logan F. McColl, Xizhao Chen, Michael D. Solga, Kailo Schlegel, Sean P. Haughey, Peter I. Lobo, Kristen Fread, Eli Zunder, Ryan Cha, Stephen Park, J. Jared Christophel, Quanjun Cui, Abhijit S. Dighe
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
BMP
macrophages
T cells
fracture healing
stem cells
type 2 immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1064238/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1064238/full

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