Targeting Cholesterol Homeostasis Improves Recovery in Experimental Optic Neuritis

Targeting Cholesterol Homeostasis Improves Recovery in Experimental Optic Neuritis

Acute optic neuritis (ON) is a common cause of vision loss and is often associated with multiple sclerosis (MS). Cholesterol recycling has been identified as a key limiting factor in recovery after demyelination events. Thus, the purpose of our study was to determine if the augmentation of cholester...

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Bibliographic Details
Main Authors: Cheyanne R. Godwin, Jeffrey J. Anders, Lin Cheng, Benjamin W. Elwood, Randy H. Kardon, Oliver W. Gramlich
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biomolecules
Subjects:
optic neuritis
multiple sclerosis
gentisic acid
EAE
electrophysiology
cholesterol recycling
Online Access:https://www.mdpi.com/2218-273X/12/10/1437

Internet

https://www.mdpi.com/2218-273X/12/10/1437

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