Inactivation of the Mouse L-Proline Transporter PROT Alters Glutamatergic Synapse Biochemistry and Perturbs Behaviors Required to Respond to Environmental Changes

Inactivation of the Mouse L-Proline Transporter PROT Alters Glutamatergic Synapse Biochemistry and Perturbs Behaviors Required to Respond to Environmental Changes

The endogenous neutral amino acid L-proline exhibits a variety of physiological and behavioral actions in the nervous system, highlighting the importance of accurately regulating its extracellular abundance. The L-proline transporter PROT (Slc6A7) is believed to control the spatial and temporal dist...

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Bibliographic Details
Main Authors: Daniel Schulz, Julia Morschel, Stefanie Schuster, Volker Eulenburg, Jesús Gomeza
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
neurotransmitter transporter
L-proline transporter
PROT
knockout mice
approach-avoidance
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00279/full

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https://www.frontiersin.org/article/10.3389/fnmol.2018.00279/full

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