Hydrogen peroxide induced cell death: One or two modes of action?

Imlay and Linn show that exposure of logarithmically growing Escherichia coli to hydrogen peroxide (H2O2) leads to two kinetically distinguishable modes of cell killing. Mode one killing is pronounced near 1 mM concentration of H2O2 and is caused by DNA damage, whereas mode-two killing requires high...

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Bibliographic Details
Main Authors: Lionel Uhl, Audrey Gerstel, Maialène Chabalier, Sam Dukan
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844015305156