Functional Ambivalence of Dendritic Cells: Tolerogenicity and Immunogenicity

Functional Ambivalence of Dendritic Cells: Tolerogenicity and Immunogenicity

Dendritic cells (DCs) are the most potent professional antigen-presenting cells (APCs) and inducers of T cell-mediated immunity. Although DCs play a central role in promoting adaptive immune responses against growing tumors, they also establish and maintain peripheral tolerance. DC activity depends...

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Bibliographic Details
Main Authors: Ji-Hee Nam, Jun-Ho Lee, So-Yeon Choi, Nam-Chul Jung, Jie-Young Song, Han-Geuk Seo, Dae-Seog Lim
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
dendritic cells
tolerogenicity
regulatory T cells
autoimmune disease
inflammatory disease
immunotherapy
Online Access:https://www.mdpi.com/1422-0067/22/9/4430

Internet

https://www.mdpi.com/1422-0067/22/9/4430

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