Structure-Function analysis of the CTLA-4 interaction with PP2A

<p>Abstract</p> <p>Background</p> <p>CTLA-4 functions primarily as an inhibitor of T cell activation. There are several candidate explanations as to how CTLA-4 modulates T cell responses, but the exact mechanism remains undefined. The tail of CTLA-4 does not have any in...

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Bibliographic Details
Main Authors: Chau Thu A, Teft Wendy A, Madrenas Joaquín
Format: Article
Language:English
Published: BMC 2009-04-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/10/23