Transcriptome analysis of AAV-induced retinopathy models expressing human VEGF, TNF-α, and IL-6 in murine eyes

Transcriptome analysis of AAV-induced retinopathy models expressing human VEGF, TNF-α, and IL-6 in murine eyes

Abstract Retinopathies are multifactorial diseases with complex pathologies that eventually lead to vision loss. Animal models facilitate the understanding of the pathophysiology and identification of novel treatment options. However, each animal model reflects only specific disease aspects and unde...

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Main Authors: Kolja Becker, Carina M. Weigelt, Holger Fuchs, Coralie Viollet, Werner Rust, Hannah Wyatt, Jochen Huber, Thorsten Lamla, Francesc Fernandez-Albert, Eric Simon, Nina Zippel, Remko A. Bakker, Holger Klein, Norbert H. Redemann
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-23065-4

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https://doi.org/10.1038/s41598-022-23065-4

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