Hap10: reconstructing accurate and long polyploid haplotypes using linked reads

Hap10: reconstructing accurate and long polyploid haplotypes using linked reads

Abstract Background Haplotype information is essential for many genetic and genomic analyses, including genotype-phenotype associations in human, animals and plants. Haplotype assembly is a method for reconstructing haplotypes from DNA sequencing reads. By the advent of new sequencing technologies,...

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Bibliographic Details
Main Authors: Sina Majidian, Mohammad Hossein Kahaei, Dick de Ridder
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Bioinformatics
Subjects:
DNA sequence analysis
Computational genetics
Haplotype
Synthetic long reads
Linked read
10X genomics
Online Access:http://link.springer.com/article/10.1186/s12859-020-03584-5

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http://link.springer.com/article/10.1186/s12859-020-03584-5

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