Comparing progression biomarkers in clinical trials of early Alzheimer’s disease

Abstract Objective To investigate the statistical power of plasma, imaging, and cognition biomarkers as Alzheimer’s disease (AD) clinical trial outcome measures. Methods Plasma neurofilament light, structural magnetic resonance imaging, and cognition were measured longitudinally in the Alzheimer’s D...

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Bibliographic Details
Main Authors: Nicholas C. Cullen, Henrik Zetterberg, Philip S. Insel, Bob Olsson, Ulf Andreasson, the Alzheimer’s Disease Neuroimaging Initiative, Kaj Blennow, Oskar Hansson, Niklas Mattsson‐Carlgren
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.51158