Transcriptional Response to Hypoxia: The Role of HIF-1-Associated Co-Regulators

Transcriptional Response to Hypoxia: The Role of HIF-1-Associated Co-Regulators

The Hypoxia Inducible Factor 1 (HIF-1) plays a major role in the cellular response to hypoxia by regulating the expression of many genes involved in adaptive processes that allow cell survival under low oxygen conditions. Adaptation to the hypoxic tumor micro-environment is also critical for cancer...

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Bibliographic Details
Main Authors: Angelos Yfantis, Ilias Mylonis, Georgia Chachami, Marios Nikolaidis, Grigorios D. Amoutzias, Efrosyni Paraskeva, George Simos
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cells
Subjects:
hypoxia
HIF-1
transcriptional regulation
chromatin
cancer
Online Access:https://www.mdpi.com/2073-4409/12/5/798

Internet

https://www.mdpi.com/2073-4409/12/5/798

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