Open-label, randomised, clinical trial to evaluate the immunogenicity and safety of a prophylactic vaccination of healthcare providers by administration of a heterologous vaccine regimen against Ebola in the Democratic Republic of the Congo: the study protocol

Introduction This article describes the protocol of an Ebola vaccine clinical trial which investigates the safety and immunogenicity of a two-dose prophylactic Ebola vaccine regimen comprised of two Ebola vaccines (Ad26.ZEBOV and MVA-BN-Filo) administered 56 days apart, followed by a booster vaccina...

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Bibliographic Details
Main Authors: Jean-Pierre Van Geertruyden, Pierre Van Damme, Ynke Larivière, Vivi Maketa, Junior Matangila, Patrick Mitashi, Jessie De Bie, Trésor Zola, Elke Stoppie, Hypolite Muhindo-Mavoko
Format: Article
Language:English
Published: BMJ Publishing Group 2021-09-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/9/e046835.full