Heterozygote Dopamine Transporter Knockout Rats Display Enhanced Cocaine Locomotion in Adolescent Females

Heterozygote Dopamine Transporter Knockout Rats Display Enhanced Cocaine Locomotion in Adolescent Females

Cocaine is a powerful psychostimulant that is one of the most widely used illicit addictive. The dopamine transporter (DAT) plays a major role in mediating cocaine’s reward effect. Decreases in DAT expression increase rates of drug abuse and vulnerability to comorbid psychiatric disorders. We used t...

Full description

Bibliographic Details
Main Authors: Marta Pardo, Michele Martin, Raul R. Gainetdinov, Deborah C Mash, Sari Izenwasser
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
dopamine transporter
cocaine
knockout
heterozygous
sex differences
addiction
Online Access:https://www.mdpi.com/1422-0067/23/23/15414

Internet

https://www.mdpi.com/1422-0067/23/23/15414

Similar Items