The proton channel OTOP1 is a sensor for the taste of ammonium chloride

Abstract Ammonium (NH4 +), a breakdown product of amino acids that can be toxic at high levels, is detected by taste systems of organisms ranging from C. elegans to humans and has been used for decades in vertebrate taste research. Here we report that OTOP1, a proton-selective ion channel expressed...

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Bibliographic Details
Main Authors: Ziyu Liang, Courtney E. Wilson, Bochuan Teng, Sue C. Kinnamon, Emily R. Liman
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41637-4