Opioids modulate an emergent rhythmogenic process to depress breathing

Opioids modulate an emergent rhythmogenic process to depress breathing

How mammalian neural circuits generate rhythmic activity in motor behaviors, such as breathing, walking, and chewing, remains elusive. For breathing, rhythm generation is localized to a brainstem nucleus, the preBötzinger Complex (preBötC). Rhythmic preBötC population activity consists of strong ins...

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Bibliographic Details
Main Authors: Xiaolu Sun, Carolina Thörn Pérez, Nagaraj Halemani D, Xuesi M Shao, Morgan Greenwood, Sarah Heath, Jack L Feldman, Kaiwen Kam
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-12-01
Series:eLife
Subjects:
opioids
breathing
rhythm generation
central pattern generator
motor systems
Online Access:https://elifesciences.org/articles/50613

Internet

https://elifesciences.org/articles/50613

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