LSD1 inhibition suppresses the growth of clear cell renal cell carcinoma via upregulating P21 signaling

LSD1 inhibition suppresses the growth of clear cell renal cell carcinoma via upregulating P21 signaling

Histone lysine-specific demethylase 1 (LSD1) has been implicated in the disease progression of several types of solid tumors. This study provides the first evidence showing that LSD1 overexpression occurred in 62.6% (224/358) of clear cell renal cell carcinomas (ccRCC). LSD1 expression was associate...

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Bibliographic Details
Main Authors: Liangsong Zhu, Jianfeng Wang, Wen Kong, Jiwei Huang, Baijun Dong, Yiran Huang, Wei Xue, Jin Zhang
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Acta Pharmaceutica Sinica B
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383518304568

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http://www.sciencedirect.com/science/article/pii/S2211383518304568

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