Analysis of CCR2 splice variant expression patterns and functional properties

Analysis of CCR2 splice variant expression patterns and functional properties

Abstract Background C–C motif chemokine receptor 2 (CCR2), the main receptor for monocyte chemoattractant protein-1 (MCP-1), is expressed on immune cells, including monocytes, macrophages, and activated T cells, and mediates cell migration toward MCP-1 in inflammation-related diseases. The CCR2 gene...

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Bibliographic Details
Main Authors: Hee-Kyung Park, Yun Hee Na, Huong Thi Nguyen, Lan Phuong Nguyen, Sunghoon Hurh, Jae Young Seong, Cheol Soon Lee, Byung-Joo Ham, Jong-Ik Hwang
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Cell & Bioscience
Subjects:
CCR2
Splice variant
MCP-1
β-Arrestin
Chemotaxis
Online Access:https://doi.org/10.1186/s13578-022-00787-6

Internet

https://doi.org/10.1186/s13578-022-00787-6

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