Inflammatory ER stress responses dictate the immunopathogenic progression of systemic candidiasis

Inflammatory ER stress responses dictate the immunopathogenic progression of systemic candidiasis

Recognition of pathogen-associated molecular patterns can trigger the inositol-requiring enzyme 1 α (IRE1α) arm of the endoplasmic reticulum (ER) stress response in innate immune cells. This process maintains ER homeostasis and also coordinates diverse immunomodulatory programs during bacterial and...

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Bibliographic Details
Main Authors: Deepika Awasthi, Sahil Chopra, Byuri A. Cho, Alexander Emmanuelli, Tito A. Sandoval, Sung-Min Hwang, Chang-Suk Chae, Camilla Salvagno, Chen Tan, Liliana Vasquez-Urbina, Jose J. Fernandez Rodriguez, Sara F. Santagostino, Takao Iwawaki, E. Alfonso Romero-Sandoval, Mariano Sanchez Crespo, Diana K. Morales, Iliyan D. Iliev, Tobias M. Hohl, Juan R. Cubillos-Ruiz
Format: Article
Language:English
Published: American Society for Clinical Investigation 2023-09-01
Series:The Journal of Clinical Investigation
Subjects:
Immunology
Infectious disease
Online Access:https://doi.org/10.1172/JCI167359

Internet

https://doi.org/10.1172/JCI167359

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