Long‐Term Administration of Eicosapentaenoic Acid Improves Post–Myocardial Infarction Cardiac Remodeling in Mice by Regulating Macrophage Polarization

Long‐Term Administration of Eicosapentaenoic Acid Improves Post–Myocardial Infarction Cardiac Remodeling in Mice by Regulating Macrophage Polarization

BackgroundConsumption of n‐3 fatty acids reduces the incidence of cardiovascular mortality in populations that consume diets rich in fish oil. Eicosapentaenoic acid (EPA) is an n‐3 fatty acid known to reduce the frequency of nonfatal coronary events; however, the frequency of mortality after myocard...

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Bibliographic Details
Main Authors: Masayuki Takamura, Keisuke Kurokawa, Hiroshi Ootsuji, Oto Inoue, Hikari Okada, Ayano Nomura, Shuichi Kaneko, Soichiro Usui
Format: Article
Language:English
Published: Wiley 2017-02-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
acute myocardial infarction
eicosapentaenoic acid
inflammation
macrophage
macrophage polarization
mouse
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.116.004560

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.116.004560

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