Molecular basis of HFE-hemochromatosis

Iron-overload disorders owing to genetic misregulation of iron acquisition are referred to as hereditary hemochromatosis (HH). The most prevalent genetic iron overload disorder in Caucasians is caused by mutations in the HFE gene, an atypical MHC class I molecule. Recent studies classified HFE/Hfe-h...

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Bibliographic Details
Main Author: Maja eVujic Spasic
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00042/full