Self-propelled nanomotor reconstructs tumor microenvironment through synergistic hypoxia alleviation and glycolysis inhibition for promoted anti-metastasis
Solid tumors always exhibit local hypoxia, resulting in the high metastasis and inertness to chemotherapy. Reconstruction of hypoxic tumor microenvironment (TME) is considered a potential therapy compared to directly killing tumor cells. However, the insufficient oxygen delivery to deep tumor and th...
Main Authors: | Wenqi Yu, Ruyi Lin, Xueqin He, Xiaotong Yang, Huilin Zhang, Chuan Hu, Rui Liu, Yuan Huang, Yi Qin, Huile Gao |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-09-01
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Series: | Acta Pharmaceutica Sinica B |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383521001337 |
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