Biomimetic proteolipid vesicles for reverting GPI deficiency in paroxysmal nocturnal hemoglobinuria

Biomimetic proteolipid vesicles for reverting GPI deficiency in paroxysmal nocturnal hemoglobinuria

Summary: Nano-vesicular carriers are promising tissue-specific drug delivery platforms. Here, biomimetic proteolipid vesicles (BPLVs) were used for delivery of glycosylphosphatidylinositol (GPI)-anchored proteins to GPI deficient paroxysmal nocturnal hemoglobinuria (PNH) cells. BPLVs were assembled...

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Bibliographic Details
Main Authors: Valentina Giudice, Pasqualina Scala, Erwin P. Lamparelli, Marisa Gorrese, Bianca Serio, Angela Bertolini, Francesca Picone, Giovanna Della Porta, Carmine Selleri
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:iScience
Subjects:
Drug delivery system
Natural sciences
Biological sciences
Biochemistry
Biomolecules
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224002426

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224002426

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