Functional Abnormality Associated With Tau Deposition in Alzheimer’s Disease – A Hybrid Positron Emission Tomography/MRI Study

Functional Abnormality Associated With Tau Deposition in Alzheimer’s Disease – A Hybrid Positron Emission Tomography/MRI Study

Objective: To investigate the characteristics of tau deposition and its impact on functional connectivity (FC) in Alzheimer’s disease (AD).Methods: Hybrid PET/MRI scans with [18F]-THK5317 and neuropsychological assessments were undertaken in 26 participants with AD and 19 healthy controls (HC). The...

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Bibliographic Details
Main Authors: Liping Fu, Zhi Zhou, Linwen Liu, Jinming Zhang, Hengge Xie, Xiaojun Zhang, Mingwei Zhu, Ruimin Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
PET/MRI
tau
fMRI
functional connectivity
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.758053/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2021.758053/full

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