How the intestinal peptide transporter PEPT-1 contributes to an obesity phenotype in Caenorhabditits elegans.

How the intestinal peptide transporter PEPT-1 contributes to an obesity phenotype in Caenorhabditits elegans.

BACKGROUND: Amino acid absorption in the form of di- and tripeptides is mediated by the intestinal proton-coupled peptide transporter PEPT-1 (formally OPT-2) in Caenorhabditits elegans. Transporter-deficient animals (pept-1(lg601)) show impaired growth, slowed postembryonal development and major cha...

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Bibliographic Details
Main Authors: Britta Spanier, Katrin Lasch, Silke Marsch, Jacqueline Benner, Wenjuan Liao, Hao Hu, Hermine Kienberger, Wolfgang Eisenreich, Hannelore Daniel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2708923?pdf=render

Internet

http://europepmc.org/articles/PMC2708923?pdf=render

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