Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation

Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation

Background: Some individuals living with obesity may be relatively metabolically healthy, whilst others suffer from multiple conditions that may be linked to adverse metabolic effects or other factors. The extent to which the adverse metabolic component of obesity contributes to disease compared to...

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Bibliographic Details
Main Authors: Susan Martin, Jessica Tyrrell, E Louise Thomas, Matthew J Bown, Andrew R Wood, Robin N Beaumont, Lam C Tsoi, Philip E Stuart, James T Elder, Philip Law, Richard Houlston, Christopher Kabrhel, Nikos Papadimitriou, Marc J Gunter, Caroline J Bull, Joshua A Bell, Emma E Vincent, Naveed Sattar, Malcolm G Dunlop, Ian PM Tomlinson, Sara Lindström, INVENT consortium, Jimmy D Bell, Timothy M Frayling, Hanieh Yaghootkar
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-01-01
Series:eLife
Subjects:
Mendelian randomisation
obesity
favourable adiposity
cardiovascular disease
cancer
Online Access:https://elifesciences.org/articles/72452

Internet

https://elifesciences.org/articles/72452

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