Astroglial glucose uptake determines brain FDG-PET alterations and metabolic connectivity during healthy aging in mice

Astroglial glucose uptake determines brain FDG-PET alterations and metabolic connectivity during healthy aging in mice

Purpose: 2-Fluorodeoxyglucose-PET (FDG-PET) is a powerful tool to study glucose metabolism in mammalian brains, but cellular sources of glucose uptake and metabolic connectivity during aging are not yet understood. Methods: Healthy wild-type mice of both sexes (2–21 months of age) received FDG-PET a...

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Bibliographic Details
Main Authors: Laura M. Bartos, Sebastian T. Kunte, Stephan Wagner, Philipp Beumers, Rebecca Schaefer, Artem Zatcepin, Yunlei Li, Maria Griessl, Leonie Hoermann, Karin Wind-Mark, Peter Bartenstein, Sabina Tahirovic, Sibylle Ziegler, Matthias Brendel, Johannes Gnörich
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:NeuroImage
Subjects:
FDG-PET
Aging
Astroglia
Metabolic connectivity
Scradiotracing
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811924003574

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http://www.sciencedirect.com/science/article/pii/S1053811924003574

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