Colistin–niclosamide-loaded nanoemulsions and nanoemulsion gels for effective therapy of colistin-resistant Salmonella infections

Colistin–niclosamide-loaded nanoemulsions and nanoemulsion gels for effective therapy of colistin-resistant Salmonella infections

Colistin (COL) is regarded as a last-resort treatment for infections by multidrug-resistant (MDR) Gram-negative bacteria. The emergence of colistin-resistant Enterobacterales poses a significant global public health concern. Our study discovered that niclosamide (NIC) reverses COL resistance in Salm...

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Bibliographic Details
Main Authors: Junkai Zhang, Xilong Wang, Pengliang Li, Yanling Gao, Ruiyun Wang, Shuaihua Li, Kaifang Yi, Xiaodie Cui, Gongzheng Hu, Yajun Zhai
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Veterinary Science
Subjects:
colistin
niclosamide
bacterial resistance
Salmonella
nanoemulsions
nanoemulsion gels
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2024.1492543/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2024.1492543/full

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