Impact of vaginal microbiome communities on HIV antiretroviral-based pre-exposure prophylaxis (PrEP) drug metabolism.

Despite the efficacy of antiretroviral-based pre-exposure prophylactics (PrEP) in men who have sex with men, studies in women have produced widely varying outcomes. Recent evidence demonstrates that vaginal microbial communities are associated with increased HIV acquisition risk and may impact PrEP...

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Bibliographic Details
Main Authors: Ryan K Cheu, Andrew T Gustin, Christina Lee, Luca Schifanella, Charlene J Miller, Avie Ha, Casey Kim, Violeta J Rodriguez, Margaret Fischl, Adam D Burgener, Kelly B Arnold, Maria L Alcaide, Nichole R Klatt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009024