Oleic acid stimulation of amino acid uptake in primary human trophoblast cells is mediated by phosphatidic acid and mTOR signaling

Abstract Normal fetal development is critically dependent on optimal nutrient supply by the placenta, and placental amino acid transport has been demonstrated to be positively associated with fetal growth. Mechanistic target of rapamycin (mTOR) is a positive regulator of placental amino acid transpo...

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Bibliographic Details
Main Authors: Elena Silva, Véronique Ferchaud‐Roucher, Anita Kramer, Lana Madi, Priyadarshini Pantham, Stephanie Chassen, Thomas Jansson, Theresa L. Powell
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:FASEB BioAdvances
Subjects:
Online Access:https://doi.org/10.1096/fba.2023-00113