Absence of the RET+3:T allele in the MTC patients
<p>Abstract</p> <p>The mutations of the RET proto-oncogene contributes to the development of MTC by increasing the activity of the receptor encoded by this gene. Variant T of polymorphism rs2435357 located in the enhancer of the RET gene reduces the enhancer’s activity. The opposit...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-10-01
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| Series: | Hereditary Cancer in Clinical Practice |
| Online Access: | http://www.hccpjournal.com/content/10/1/14 |