Clinical characteristics and treatment outcomes in six cases of malignant tenosynovial giant cell tumor: initial experience of molecularly targeted therapy

Clinical characteristics and treatment outcomes in six cases of malignant tenosynovial giant cell tumor: initial experience of molecularly targeted therapy

Abstract Background Although tenosynovial giant cell tumor (TGCT) is classified as a benign tumor, it may undergo malignant transformation and metastasize in extremely rare occasions. High aberrant expression of CSF1 has been implicated in the development of TGCT and recent studies have shown promis...

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Bibliographic Details
Main Authors: Robert Nakayama, Jyothi Priya Jagannathan, Nikhil Ramaiya, Marco L. Ferrone, Chandrajit P. Raut, John E. Ready, Jason L. Hornick, Andrew J. Wagner
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Cancer
Subjects:
Tenosynovial giant cell tumor
Malignant tenosynovial giant cell tumor
Malignant transformation
Soft tissue sarcoma
Metastasis
Chemotherapy
Online Access:http://link.springer.com/article/10.1186/s12885-018-5188-6

Internet

http://link.springer.com/article/10.1186/s12885-018-5188-6

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