miR-582-5p Is a Tumor Suppressor microRNA Targeting the Hippo-YAP/TAZ Signaling Pathway in Non-Small Cell Lung Cancer

miR-582-5p Is a Tumor Suppressor microRNA Targeting the Hippo-YAP/TAZ Signaling Pathway in Non-Small Cell Lung Cancer

The Hippo-YAP/TAZ signaling pathway is an evolutionarily conserved signaling pathway involved in a broad spectrum of biological processes, including tumorigenesis. Whilst aberrant Hippo-YAP/TAZ signaling is frequently reported in various cancers, the genetic alterations of this pathway are relativel...

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Bibliographic Details
Main Authors: Bowen Zhu, Mitheera V, Megan Finch-Edmondson, Yaelim Lee, Yue Wan, Marius Sudol, Ramanuj DasGupta
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
miR-582-5p
Hippo
YAP (Yes-associated protein or YAP1)
TAZ (Transcriptional co-activator with PDZ-binding motif aka WWTR1)
NSCLC (Non-small Cell Lung Cancer)
Online Access:https://www.mdpi.com/2072-6694/13/4/756

Internet

https://www.mdpi.com/2072-6694/13/4/756

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