Bystander activated CD8+ T cells mediate neuropathology during viral infection via antigen-independent cytotoxicity

Bystander activated CD8+ T cells mediate neuropathology during viral infection via antigen-independent cytotoxicity

Abstract Although many viral infections are linked to the development of neurological disorders, the mechanism governing virus-induced neuropathology remains poorly understood, particularly when the virus is not directly neuropathic. Using a mouse model of Zika virus (ZIKV) infection, we found that...

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Bibliographic Details
Main Authors: Elizabeth Balint, Emily Feng, Elizabeth C. Giles, Tyrah M. Ritchie, Alexander S. Qian, Fatemeh Vahedi, Amelia Montemarano, Ana L. Portillo, Jonathan K. Monteiro, Bernardo L. Trigatti, Ali A. Ashkar
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44667-0

Internet

https://doi.org/10.1038/s41467-023-44667-0

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