Transport engineering for improving the production and secretion of valuable alkaloids in Escherichia coli

Transport engineering for improving the production and secretion of valuable alkaloids in Escherichia coli

Microorganisms can be metabolically engineered to produce specialized plant metabolites. However, these methods are limited by low productivity and intracellular accumulation of metabolites. We sought to use transport engineering for producing reticuline, an important intermediate in the alkaloid bi...

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Bibliographic Details
Main Authors: Yasuyuki Yamada, Miya Urui, Hidehiro Oki, Kai Inoue, Haruyuki Matsui, Yoshito Ikeda, Akira Nakagawa, Fumihiko Sato, Hiromichi Minami, Nobukazu Shitan
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Metabolic Engineering Communications
Subjects:
Alkaloids
Metabolic engineering
Transport engineering
E. coli
Reticuline
AtDTX1
Online Access:http://www.sciencedirect.com/science/article/pii/S2214030121000249

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http://www.sciencedirect.com/science/article/pii/S2214030121000249

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