Endoplasmic reticulum stress as a novel target to inhibit transdifferentiation of human retinal pigment epithelial cells
Background: The epithelial to mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells is a critical event in the pathogenesis of proliferative vitreoretinopathy and neovascular age-related macular degeneration, which are the leading causes of severe vision loss. Endoplasmic reticulum...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
IMR Press
2022-01-01
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Series: | Frontiers in Bioscience-Landmark |
Subjects: | |
Online Access: | https://www.imrpress.com/journal/FBL/27/2/10.31083/j.fbl2702038 |