Experimental evidence for UNC-6 (netrin) axon guidance by stochastic fluctuations of intracellular UNC-40 (DCC) outgrowth activity
Summary How the direction of axon guidance is determined is not understood. In Caenorhabditis elegans the UNC-40 (DCC) receptor mediates a response to the UNC-6 (netrin) guidance cue that directs HSN axon development. UNC-40 becomes asymmetrically localized within the HSN neuron to the site of axon...
Main Authors: | , , , , , , |
---|---|
格式: | 文件 |
语言: | English |
出版: |
The Company of Biologists
2013-10-01
|
丛编: | Biology Open |
主题: | |
在线阅读: | http://bio.biologists.org/content/2/12/1300 |