Mastoparan M promotes functional recovery in stroke mice by activating autophagy and inhibiting ferroptosis

Mastoparan M promotes functional recovery in stroke mice by activating autophagy and inhibiting ferroptosis

Neuronal ferroptosis and autophagy are crucial in the pathogenesis of cerebral ischemia-reperfusion injury (CIRI). Mastoparan M (Mast-M), extracted from the crude venom of Vespa magnifica (Smith), comprises 14 amino acid residues. Previous studies suggested that Mast-M reduces neuronal damage follow...

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Bibliographic Details
Main Authors: Qian Wang, Chaojie Liu, Mingran Chen, Jie Zhao, Dexiao Wang, Pengfei Gao, Chenggui Zhang, Hairong Zhao
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Mastoparan M
GPX4
NRF2
Ferroptosis
Autophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222400444X

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http://www.sciencedirect.com/science/article/pii/S075333222400444X

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