Method transfer from ion pair chromatography to charged aerosol detector-compatible mixed-mode chromatography: A case study using carbocisteine
To take advantage of the charged aerosol detector (CAD) for sensitive LC analysis of analytes with weak chromophore, the volatility of the entire mobile phase is a prerequisite. Therefore, it is not feasible to use common non-volatile ion-pairing reagents such as tetrabutylammonium hydroxide for the...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-11-01
|
| Series: | Journal of Chromatography Open |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772391721000141 |