Development of GABARAP family protein-sensitive LIR-based probes for neuronal autophagy

Development of GABARAP family protein-sensitive LIR-based probes for neuronal autophagy

Abstract Autophagy allows for lysosomal cellular degradation of cytosolic components. In particular, neuronal autophagy is essential for cellular homeostasis and neuronal survival and is tightly regulated by several autophagy-related (ATG) proteins in post-mitotic neurons. Among these ATG proteins,...

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Bibliographic Details
Main Authors: Pureum Jeon, Ju-Hui Park, Yong-Woo Jun, You-Kyung Lee, Deok-Jin Jang, Jin-A Lee
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Molecular Brain
Subjects:
LC3
GABARAP
LIR motif
Autophagy
Online Access:http://link.springer.com/article/10.1186/s13041-019-0458-z

Internet

http://link.springer.com/article/10.1186/s13041-019-0458-z

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