Assessment of technical and clinical utility of a bead-based flow cytometry platform for multiparametric phenotyping of CNS-derived extracellular vesicles

Assessment of technical and clinical utility of a bead-based flow cytometry platform for multiparametric phenotyping of CNS-derived extracellular vesicles

Abstract Background Extracellular vesicles (EVs) originating from the central nervous system (CNS) can enter the blood stream and carry molecules characteristic of disease states. Therefore, circulating CNS-derived EVs have the potential to serve as liquid-biopsy markers for early diagnosis and foll...

Full description

Bibliographic Details
Main Authors: Alexandra Brahmer, Carsten Geiß, Andriani Lygeraki, Elmo Neuberger, Theophilos Tzaridis, Tinh Thi Nguyen, Felix Luessi, Anne Régnier-Vigouroux, Gunther Hartmann, Perikles Simon, Kristina Endres, Stefan Bittner, Katrin S. Reiners, Eva-Maria Krämer-Albers
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Cell Communication and Signaling
Subjects:
Extracellular vesicles
CNS diseases
EV phenotyping
Flow cytometry
Biomarker
Glioblastoma
Online Access:https://doi.org/10.1186/s12964-023-01308-9

Internet

https://doi.org/10.1186/s12964-023-01308-9

Similar Items