Anti-Inflammatory Activity of <i>N</i>′-(3-(1H-indol-3-yl)benzylidene)-2-cyanoacetohydrazide Derivative via sGC-NO/Cytokine Pathway

Anti-Inflammatory Activity of <i>N</i>′-(3-(1H-indol-3-yl)benzylidene)-2-cyanoacetohydrazide Derivative via sGC-NO/Cytokine Pathway

The <i>N</i>-acylhydrazone function has been reported as a pharmacophore group of molecules with diverse pharmacological activities, including anti-inflammatory effects. Therefore, this study was designed to evaluate the anti-inflammatory potential of the compound <i>N</i>′-(...

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Bibliographic Details
Main Authors: Pablo Rayff da Silva, Nadjaele de Melo Apolinário, Simone Ângela Soares da Silva, Maria Elaine Cristina Araruna, Thássia Borges Costa, Yvnni M. S. de Medeiros e Silva, Teresinha Gonçalves da Silva, Ricardo Olímpio de Moura, Vanda Lucia dos Santos
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Pharmaceuticals
Subjects:
cytokines
leukocyte migration
<i>N</i>-acylhydrazones
nitric oxide
JR19
Online Access:https://www.mdpi.com/1424-8247/16/10/1415

Internet

https://www.mdpi.com/1424-8247/16/10/1415

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