Evolution of highly pathogenic H5N1 influenza A virus in the central nervous system of ferrets.

Evolution of highly pathogenic H5N1 influenza A virus in the central nervous system of ferrets.

Central nervous system (CNS) disease is the most common extra-respiratory tract complication of influenza A virus infections in humans. Remarkably, zoonotic highly pathogenic avian influenza (HPAI) H5N1 virus infections are more often associated with CNS disease than infections with seasonal influen...

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Bibliographic Details
Main Authors: Jurre Y Siegers, Lucas Ferreri, Dirk Eggink, Edwin J B Veldhuis Kroeze, Aartjan J W Te Velthuis, Marco van de Bildt, Lonneke Leijten, Peter van Run, Dennis de Meulder, Theo Bestebroer, Mathilde Richard, Thijs Kuiken, Anice C Lowen, Sander Herfst, Debby van Riel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011214

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https://doi.org/10.1371/journal.ppat.1011214

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