Genistein‐Calcitriol Mitigates Hyperosmotic Stress‐Induced TonEBP, CFTR Dysfunction, VDR Degradation and Inflammation in Dry Eye Disease

Genistein‐Calcitriol Mitigates Hyperosmotic Stress‐Induced TonEBP, CFTR Dysfunction, VDR Degradation and Inflammation in Dry Eye Disease

Dry eye disease (DED) signs and symptoms are causally associated with increased ocular surface (OS) inflammation. Modulation of key regulators of aberrant OS inflammation is of interest for clinical management. We investigated the status and the potential to harness key endogenous protective factors...

Full description

Bibliographic Details
Main Authors: Trailokyanath Panigrahi, Sharon D’Souza, Rohit Shetty, Archana Padmanabhan Nair, Anuprita Ghosh, Everette Jacob Remington Nelson, Arkasubhra Ghosh, Swaminathan Sethu
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.12858

Internet

https://doi.org/10.1111/cts.12858

Similar Items