Poloxamer 188 Attenuates Ischemia-Reperfusion-Induced Lung Injury by Maintaining Cell Membrane Integrity and Inhibiting Multiple Signaling Pathways

Poloxamer 188 Attenuates Ischemia-Reperfusion-Induced Lung Injury by Maintaining Cell Membrane Integrity and Inhibiting Multiple Signaling Pathways

Background: Poloxamer 188 (P188) possesses anti-inflammatory properties and can help to maintain plasma membrane function. P188 has been reported to exert beneficial effects in the treatment of various disorders. However, the effects of P188 in ischemia/reperfusion (IR)-induced acute lung injury hav...

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Bibliografski detalji
Glavni autori: Shih-En Tang, Wen-I Liao, Hsin-Ping Pao, Chin-Wang Hsu, Shu-Yu Wu, Kun-Lun Huang, Shi-Jye Chu
Format: Članak
Jezik:English
Izdano: Frontiers Media S.A. 2021-07-01
Serija:Frontiers in Pharmacology
Teme:
acute lung injury
ischemia-reperfusion
poloxamer 188
hypoxia/reoxygenation
membrane integrity
Online pristup:https://www.frontiersin.org/articles/10.3389/fphar.2021.650573/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.650573/full

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