The germinal center antibody response in health and disease [version 1; referees: 2 approved]
The germinal center response is the delayed but sustained phase of the antibody response that is responsible for producing high-affinity antibodies of the IgG, IgA and/or IgE isotypes. B cells in the germinal center undergo re-iterative cycles of somatic hypermutation of immunoglobulin gene variable...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2016-05-01
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| Series: | F1000Research |
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| Online Access: | http://f1000research.com/articles/5-999/v1 |