Dynamic Assay for Profiling Anti-SARS-CoV-2 Antibodies and Their ACE2/Spike RBD Neutralization Capacity

Dynamic Assay for Profiling Anti-SARS-CoV-2 Antibodies and Their ACE2/Spike RBD Neutralization Capacity

Serological assays have been widely employed during the coronavirus disease 2019 (COVID-19) pandemic to measure antibody responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and to track seroconversion in populations. However, currently available assays do not allow determinatio...

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Bibliographic Details
Main Authors: Thomas Phelan, Jean Dunne, Niall Conlon, Clíona Ní Cheallaigh, W. Mark Abbott, Raquel Faba-Rodriguez, Fatima Amanat, Florian Krammer, Mark A. Little, Gerry Hughes, Colm Bergin, Colm Kerr, Sudharshana Sundaresan, Aideen Long, William McCormack, Gareth Brady
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Viruses
Subjects:
antibody
enzyme-linked immunosorbent assay
neutralization
SARS-CoV-2
serology
pseudovirus infection model
Online Access:https://www.mdpi.com/1999-4915/13/7/1371

Internet

https://www.mdpi.com/1999-4915/13/7/1371

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