Chronic stress physically spares but functionally impairs innate-like invariant T cells

Chronic stress physically spares but functionally impairs innate-like invariant T cells

Summary: The deleterious effects of psychological stress on mainstream T lymphocytes are well documented. However, how stress impacts innate-like T cells is unclear. We report that long-term stress surprisingly abrogates both T helper 1 (TH1)- and TH2-type responses orchestrated by invariant natural...

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Bibliographic Details
Main Authors: Patrick T. Rudak, Joshua Choi, Katie M. Parkins, Kelly L. Summers, Dwayne N. Jackson, Paula J. Foster, Anton I. Skaro, Ken Leslie, Vivian C. McAlister, Vijay K. Kuchroo, Wataru Inoue, Olivier Lantz, S.M. Mansour Haeryfar
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Cell Reports
Subjects:
psychological stress
innate immunity
iNKT cells
MAIT cells
cytotoxicity
habituation
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472100293X

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http://www.sciencedirect.com/science/article/pii/S221112472100293X

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