Apamin does not inhibit human cardiac Na+ current, L-type Ca2+ current or other major K+ currents.

<h4>Background</h4>Apamin is commonly used as a small-conductance Ca2+-activated K+ (SK) current inhibitor. However, the specificity of apamin in cardiac tissues remains unclear.<h4>Objective</h4>To test the hypothesis that apamin does not inhibit any major cardiac ion curren...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän: Chih-Chieh Yu, Tomohiko Ai, James N Weiss, Peng-Sheng Chen
Materialtyp: Artikel
Språk:English
Publicerad: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS ONE
Länkar:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0096691&type=printable