What are the treatment remission, response and extent of improvement rates after up to four trials of antidepressant therapies in real-world depressed patients? A reanalysis of the STAR*D study’s patient-level data with fidelity to the original research protocol

Objective Reanalyse the patient-level data set of the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study with fidelity to the original research protocol and related publications.Design The study was open label and semirandomised examining the effectiveness of up to four optimised...

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Bibliographic Details
Main Authors: Irving Kirsch, H Edmund Pigott, Thomas Kim, Colin Xu, Jay Amsterdam
Format: Article
Language:English
Published: BMJ Publishing Group 2023-07-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/7/e063095.full